Hardware / Software Architectural and Technological Exploration for Energy-Efficient and Reliable Biomedical Devices

Nowadays, the ubiquity of smart appliances in our everyday lives is increasingly strengthening the links between humans and machines. Beyond making our lives easier and more convenient, smart devices are now playing an important role in personalized healthcare delivery. This technological breakthrough is particularly relevant in a world where population aging and unhealthy habits have made non-communicable diseases the first leading cause of death worldwide according to international public health organizations. In this context, smart health monitoring systems termed Wireless Body Sensor Nodes (WBSNs), represent a paradigm shift in the healthcare landscape by greatly lowering the cost of long-term monitoring of chronic diseases, as well as improving patients' lifestyles. WBSNs are able to autonomously acquire biological signals and embed on-node Digital Signal Processing (DSP) capabilities to deliver clinically-accurate health diagnoses in real-time, even outside of a hospital environment. Energy efficiency and reliability are fundamental requirements for WBSNs, since they must operate for extended periods of time, while relying on compact batteries. These constraints, in turn, impose carefully designed hardware and software architectures for hosting the execution of complex biomedical applications. In this thesis, I develop and explore novel solutions at the architectural and technological level of the integrated circuit design domain, to enhance the energy efficiency and reliability of current WBSNs. Firstly, following a top-down approach driven by the characteristics of biomedical algorithms, I perform an architectural exploration of a heterogeneous and reconfigurable computing platform devoted to bio-signal analysis. By interfacing a shared Coarse-Grained Reconfigurable Array (CGRA) accelerator, this domain-specific platform can achieve higher performance and energy savings, beyond the capabilities offered by a baseline multi-processor system. More precisely, I propose three CGRA architectures, each contributing differently to the maximization of the application parallelization. The proposed Single, Multi and Interleaved-Datapath CGRA designs allow the developed platform to achieve substantial energy savings of up to 37%, when executing complex biomedical applications, with respect to a multi-core-only platform. Secondly, I investigate how the modeling of technology reliability issues in logic and memory components can be exploited to adequately adjust the frequency and supply voltage of a circuit, with the aim of optimizing its computing performance and energy efficiency. To this end, I propose a novel framework for workload-dependent Bias Temperature Instability (BTI) impact analysis on biomedical application results quality. Remarkably, the framework is able to determine the range of safe circuit operating frequencies without introducing worst-case guard bands. Experiments highlight the possibility to safely raise the frequency up to 101% above the maximum obtained with the classical static timing analysis. Finally, through the study of several well-known biomedical algorithms, I propose an approach allowing energy savings by dynamically and unequally protecting an under-powered data memory in a new way compared to regular error protection schemes. This solution relies on the Dynamic eRror compEnsation And Masking (DREAM) technique that reduces by approximately 21% the energy consumed by traditional error correction codes

Energy vs. Reliability Trade-offs Exploration in Biomedical Ultra-Low Power Devices

State-of-the-art wearable devices such as embedded biomedical monitoring systems apply voltage scaling to lower as much as possible their energy consumption and achieve longer battery lifetimes. While embedded memories often rely on Error Correction Codes (ECC) for error protection, in this paper we explore how the characteristics of biomedical applications can be exploited to develop new techniques with lower power overhead. We then introduce the Dynamic eRror compEnsation And Masking (DREAM) technique, that provides partial memory protection with less area and power overheads than ECC. Different tradeoffs between the error correction ability of the techniques and their energy consumption are examined to conclude that, when properly applied, DREAM consumes 21% less energy than a traditional ECC with Single Error Correction and Double Error Detection (SEC/DED) capabilities

HEAL-WEAR: an Ultra-Low Power Heterogeneous System for Bio-Signal Analysis

Personalized healthcare devices enable low-cost, unobtrusive and long-term acquisition of clinically-relevant biosignals. These appliances, termed Wireless Body Sensor Nodes (WBSNs), are fostering a revolution in health monitoring for patients affected by chronic ailments. Nowadays, WBSNs often embed complex digital processing routines, which must be performed within an extremely tight energy budget. Addressing this challenge, in this paper we introduce a novel computing architecture devoted to the ultra-low power analysis of biosignals. Its heterogeneous structure comprises multiple processors interfaced with a shared acceleration resource, implemented as a Coarse Grained Reconfigurable Array (CGRA). The CGRA mesh effectively supports the execution of the intensive loops that characterize bio-signal analysis applications, while requiring a low reconfiguration overhead. Moreover, both the processors and the reconfigurable fabric feature Single-Instruction / Multiple- Data (SIMD) execution modes, which increase efficiency when multiple data streams are concurrently processed. The run-time behavior on the system is orchestrated by a light-weight hardware mechanism, which concurrently synchronizes processors for SIMD execution and regulates access to the reconfigurable accelerator. By jointly leveraging run-time reconfiguration and SIMD execution, the illustrated heterogeneous system achieves, when executing complex bio-signal analysis applications, speedups of up to 11.3x on the considered kernels and up to 37.2% overall energy savings, with respect to an ultra-low power multicore platform which does not feature CGRA acceleration

A Multi-Core Reconfigurable Architecture for Ultra-Low Power Bio-Signal Analysis

This paper introduces a novel computing architecture devoted to the ultra-low power analysis of multiple bio-signals. Its structure comprises several processors interfaced with a shared acceleration resource, implemented as a Coarse Grained Reconfigurable Array (CGRA). The CGRA supports the efficient execution of the computationally intensive kernels present in this application domain, while requiring a low reconfiguration overhead. The run-time behavior of the resulting heterogeneous system is orchestrated by a light-weight hardware mechanism, which concurrently synchronizes processors and regulates access to the reconfigurable accelerator. The architecture achieves speed-ups of up to 11x on different bio-signal processing kernels and system-level energy savings of up to 18.6%, with respect to a multi-core platform, which does not feature CGRA acceleration

An Inexact Ultra-low Power Bio-signal Processing Architecture With Lightweight Error Recovery

The energy efficiency of digital architectures is tightly linked to the voltage level (Vdd) at which they operate. Aggressive voltage scaling is therefore mandatory when ultra-low power processing is required. Nonetheless, the lowest admissible Vdd is oen bounded by reliability concerns, especially since static and dynamic non-idealities are exacerbated in the near-threshold region, imposing costly guard-bands to guarantee correctness under worst-case conditions. A striking alternative, explored in this paper, waives the requirement for unconditional correctness, undergoing more relaxed constraints. First, aer a run-time failure, processing correctly resumes at a later point in time. Second, failures induce a limited Quality-of-Service (QoS) degradation. We focus our investigation on the practical scenario of embedded bio-signal analysis, a domain in which energy efficiency is key, while applications are inherently error-tolerant to a certain degree. Targeting a domain-specific multi-core platform, we present a study of the impact of inexactness on application-visible errors. en, we introduce a novel methodology to manage them, which requires minimal hardware resources and a negligible energy overhead. Experimental evidence show that, by tolerating 900 errors/hour, the resulting inexact platform can achieve an efficiency increase of up to 24%, with a QoS degradation of less than 3%

i-DPs CGRA: An Interleaved-Datapaths Reconfigurable Accelerator for Embedded Bio-signal Processing

Smart edge sensors for bio-signal monitoring must support complex signal processing routines within an extremely small energy envelope. Coarse-Grained Reconfigurable Arrays (CGRAs) are good candidates for tackling these conflicting objectives because, thanks to their flexibility and high computational density, they can efficiently support the computational hot-spots characterizing bio-DSP applications. The Interleaved- Datapaths (i-DPs) CGRA presented in this paper further leverages the benefits of this architectural paradigm, focusing on ultralow energy operation. Its defining feature is the complex design of its computing cells, which, by embedding multiple i-DPs, allow a high ratio between computing and control logic, effectively speeding up computations, and resulting in a marginal impact on the required IC area. Interleaved datapaths increase the energy efficiency of up to 33 %, with respect to a single-DP alternative, when executing common kernels in the multi-lead ECG signal processing field